Fabric Genomics’ high-speed interpretation platform provides more actionable results from whole genome and exome analysis
Up to 15% of infants in the United States require neonatal intensive care services, and up to 1/3 of these cases are diagnosed with underlying genetic conditions. Whole genome or exome sequencing can provide accurate and reliable results in children’s hospitals, leading to early intervention and superior pediatric outcomes. Fabric Genomics enables rapid and precise results, which is extremely critical for infants, especially those in the NICU and PICU.
See how Fabric Genomics enables rapid interpretation of whole genome sequencing at Rady Children’s Hospital.
Robust data interpretation is critical to accurately identify genomic variants and deliver maximum diagnostic yield. Typical genome interpretation methods focus on filtering to identify and prioritize variants. Fabric Enterprise is an artificial intelligence (AI)-driven platform that combines deep phenotype and genotype data, enabling labs to achieve diagnostic yields ~2X compared to the industry standard (~50% vs. 25-30%, respectively). Plus, Fabric Enterprise is always up to date with the latest reference data and standard guidelines to enable accurate variant interpretation and classification.
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A limiting factor for exome or whole genome sequencing is the time between sample collection and results reported. This turnaround time (TAT) is influenced by multiple factors, including diagnostic methodology and on-site resources.
Fabric Enterprise is an all-in-one platform for secondary analysis, interpretation, and reporting. Fabric Enterprise employs proven AI-driven prioritization to deliver a rapid TAT from VCF data to clinical results.
Fast, AI-driven analysis greatly reduces the amount of time needed to analyze each case, allowing your staff to focus on the most likely causative candidates first — and report more cases in less time.
Fabric Enterprise is designed to support all NGS-based diagnostic tests regardless of test type or scale. Starting from either raw data or variant calls from whole genome, exome, or panel tests, Fabric Enterprise provides efficient workflows for genome annotation, interpretation, clinical report generation, and sign-off. And Fabric’s scalable cloud solution incorporates comprehensive data and network security protocols.
Fabric Enterprise is built for ease of use so you can focus on getting results rather than getting help
See how Fabric Genomics enables rapid interpretation of whole genome sequence data at Rady Children’s Hospital.
Kataryzna Ellsworth, PhD FACMG discusses implementation and scaling of rapid genome testing at Rady Children’s Hospital
